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Multiscale spatial mapping of cell populations across anatomical sites in healthy human skin and basal cell carcinoma

2 Jan 2024

Abstract excerpt

Our understanding of how human skin cells differ according to anatomical site and tumour formation is limited. To address this, we have created a multiscale spatial atlas of healthy skin and basal cell carcinoma (BCC), incorporating in vivo optical coherence tomography, single-cell RNA sequencing, spatial global transcriptional profiling, and in situ sequencing. Computational spatial deconvolution and projection...

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PMID: 38165934
DOI: 10.1073/pnas.2313326120

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