Article
Is Precision Surgery Applicable to Colorectal Liver Metastases? A Systematic Review and Meta-analysis of Studies that Investigate the Association of Surgical Technique with Outcomes in the Context of Distinct Tumor Biology.
Annals of surgical oncology - 1 Mar 2024
Pikoulis Emmanouil, Papaconstantinou Dimitrios, Pikouli Anastasia, Pararas Nikolaos, Buettner Stefan, Wang Jane, Stasinos Georgios, Belias Michail, Dellaportas Dionysios, Pozios Ioannis, Antoniou Efstathios, Beyer Katharina, Kreis Martin E, Pawlik Timothy M, Margonis Georgios Antonios
Abstract excerpt
BACKGROUND: Although some data suggest that patients with mutRAS colorectal liver metastases (CRLM) may benefit from anatomic hepatectomy, this topic remains controversial. We performed a systematic review and meta-analysis to determine whether RAS mutation status was associated with prognosis relative to surgical technique [anatomic resection (AR) vs. nonanatomic resection (NAR)] among patients with CRLM....
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