Article
Cross-linking breast tumor transcriptomic states and tissue histology.
Cell reports. Medicine - 19 Dec 2023
Dawood Muhammad, Eastwood Mark, Jahanifar Mostafa, Young Lawrence, Ben-Hur Asa, Branson Kim, Jones Louise, Rajpoot Nasir, Minhas Fayyaz Ul Amir Afsar
Abstract excerpt
Identification of the gene expression state of a cancer patient from routine pathology imaging and characterization of its phenotypic effects have significant clinical and therapeutic implications. However, prediction of expression of individual genes from whole slide images (WSIs) is challenging due to co-dependent or correlated expression of multiple genes. Here, we use a purely data-driven approach to first...
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