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Article

Treatment of Non-Small Cell Lung Cancer with Atypical EGFR Mutations.

Current treatment options in oncology - 1 Dec 2023

Wells Leah, Qin Angel

Abstract excerpt

OPINION STATEMENT: EGFR tyrosine kinase inhibitors (TKI) should always be considered when treating advanced/metastatic non-small cell lung cancer (NSCLC) with atypical EGFR mutations. The first choice of TKI depends on the specific mutation(s) present and its effect on structure and function of the EGFR protein. Afatinib is the only EGFR TKI currently FDA approved for atypical EGFR mutations and has the strongest...

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PMID: 38095779
DOI: 10.1007/s11864-023-01159-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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