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Polymorphisms of the NCF4 Gene Increase the Risk of Chronic Heart Failure in Patients with Type 2 Diabetes Mellitus.

Bulletin of experimental biology and medicine - 1 Nov 2023

Azarova Yu E, Klyosova E Yu, Ivakin V E, Churilin M I, Kolomoets I I, Sunyaykina O A, Ragulina V A, Polonikov A V

Abstract excerpt

We showed for the first time that polymorphisms rs2075938 and rs2075938 of the NCF4 gene are associated with the risk of chronic heart failure in patients with type 2 diabetes mellitus (n=1310). In particular, haplotypes ATGTCTAT (OR=1.74, 95%CI=1.23-2.47; p=0.0017) and ATATTCAC (OR=2.83, 95%CI=1.33-6.03; p=0.0072) of NCF4 increase the risk of chronic heart failure in type 2 diabetes mellitus patients. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38085396
DOI: 10.1007/s10517-023-05974-0

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