Article
Comparison of Allogeneic Transplant Outcomes Between Matched Sibling Donors and Alternative Donors in Patients Over 50 Years of Age with Acute Myeloid Leukemia: 8/8 Allele-Matched Unrelated Donors and Unrelated Cord Blood Provide Better Leukemia-Free Survival Compared with Matched Sibling Donors During Nonremission Status.
Transplantation and cellular therapy - 1 Feb 2024
Konuma Takaaki, Yamasaki Satoshi, Ishiyama Ken, Mizuno Shohei, Hayashi Hiromi, Uchida Naoyuki, Shimabukuro Masashi, Tanaka Masatsugu, Kuriyama Takuro, Onizuka Makoto, Ishiwata Kazuya, Sawa Masashi, Tanaka Takashi, Ohigashi Hiroyuki, Fujiwara Shin-Ichiro, Matsuoka Ken-Ichi, Ota Shuichi, Nishida Tetsuya, Kanda Yoshinobu, Fukuda Takahiro, Atsuta Yoshiko, Nakasone Hideki, Yanada Masamitsu
Abstract excerpt
Acute myeloid leukemia (AML) is the most common indication for allogeneic hematopoietic cell transplantation (HCT). The increased availability of alternative donor sources has broadened donor types for older patients without HLA-matched sibling donors (MSD). It is uncertain if an MSD should be the first option for allogeneic HCT in patients with AML over 50 years of age. The objective of this study was to compare...
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