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Article

Mitochondrial DNA Haplogroup K Is Protective Against Autism Spectrum Disorder Risk in Populations of European Ancestry.

Journal of the American Academy of Child and Adolescent Psychiatry - 1 Aug 2024

Chang Xiao, Qu Hui-Qi, Liu Yichuan, Glessner Joseph T, Hakonarson Hakon

Abstract excerpt

OBJECTIVE: Accumulative evidence indicates a critical role of mitochondrial function in autism spectrum disorders (ASD), implying that ASD risk may be linked to mitochondrial dysfunction due to DNA (mtDNA) variations. Although a few studies have explored the association between mtDNA variations and ASD, the role of mtDNA in ASD is still unclear. Here, we aimed to investigate whether mitochondrial DNA haplogroups...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38072244
DOI: 10.1016/j.jaac.2023.09.550
PMCID: PMC11186604

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