Article
Presence of crown-like structures in breast adipose tissue; differences between healthy controls, BRCA1/2 gene mutation carriers and breast cancer patients.
Breast cancer research and treatment - 1 Feb 2024
Zwager Mieke C, Holt-Kedde Iris, Timmer-Bosscha Hetty, de Bock Geertruida H, Werker Paul M N, Schröder Carolien P, van der Vegt Bert, Arjaans Marlous
Abstract excerpt
PURPOSE: Crown-like structures (CLS) in breast adipose tissue are associated with inflammation and a potential factor in breast cancer behaviour. Whether this effect varies between breast cancer subtypes and is influenced by BMI and BRCA mutation status is presently unknown. Therefore, we compared CLS presence between adipose tissue of healthy controls, BRCA1/2 gene mutation carriers and breast cancer patients,...
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