Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Living donor liver transplantation for myocerebrohepatopathy spectrum due to POLG mutations.

Pediatric transplantation - 1 Feb 2024

Kadohisa Masashi, Okamoto Tatsuya, Yamamoto Miki, Uebayashi Elena Yukie, Sonoda Mari, Ogawa Eri, Yokoyama Atsushi, Kawasaki Hidenori, Hiejima Eitaro, Ito Shogo, Togawa Takao, Imagawa Kazuo, Murayama Kei, Okajima Hideaki, Hatano Etsuro

Abstract excerpt

BACKGROUND: POLG is one of several nuclear genes associated with mitochondrial DNA maintenance defects and is a group of diseases caused by mitochondrial DNA deficiency that results in impaired adenosine triphosphate production and organ dysfunction. Myocerebrohepatopathy spectrum (MCHS) is the most severe and earliest presentation of POLG mutations, and liver transplantation (LT) for MCHS has never been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Directed DNA Polymerase
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Polymerase gamma

Share to Infant

Share to Infant, Newborn

Share to Liver Failure, Acute

Share to Liver Transplantation

Share to Living Donors

Source

Identifiers

PMID: 38012111
DOI: 10.1111/petr.14659

Genes

POLG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Living donor liver transplantation for myocerebrohepatopathy spectrum due to POLG mutations.PMID 38012111Read ↗

Myocerebrohepatopathy spectrum disorder due to POLG mutations: A clinicopathological report.Semantic proximity Read ↗

Clinical and molecular basis of hepatocerebral mitochondrial DNA depletion syndrome in Japan: evaluation of outcomes after liver transplantation.Semantic proximity Read ↗

Clinical and molecular basis of hepatocerebral mitochondrial DNA depletion syndrome in Japan: Evaluation of outcomes after liver transplantationSemantic proximity Read ↗

Mitochondrial hepatopathies: advances in genetics and pathogenesis.Semantic proximity Read ↗

Hepatobiliary disease in XLMTM. A common comorbidity with potential impact on treatment strategiesSemantic proximity Read ↗

The clinical spectrum and natural history of early-onset diseases due to DNA polymerase gamma mutations.Semantic proximity Read ↗

Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE)-like phenotype in a patient with a novel heterozygous POLG mutation.Semantic proximity Read ↗

Acute liver failure after valproate exposure in patients with POLG1 mutations and the prognosis after liver transplantation.Semantic proximity Read ↗

Allogeneic haematopoietic stem cell transplantation for mitochondrial neurogastrointestinal encephalomyopathySemantic proximity Read ↗

Macroscopic Characteristics of the Native Liver in Children With MPV17-Related Mitochondrial DNA Depletion Syndrome: An Indication for Performing Liver Transplantation?Semantic proximity Read ↗

Muscle glycogenosis and mitochondrial hepatopathy in an infant with mutations in both the myophosphorylase and deoxyguanosine kinase genes.Semantic proximity Read ↗

Polymerase gamma deficiency (POLG): clinical course in a child with a two stage evolution from infantile myocerebrohepatopathy spectrum to an Alpers syndrome and neuropathological findings of Leigh's encephalopathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.