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Article

GPX3 Variant Genotype Affects the Risk of Developing Severe Forms of COVID-19.

International journal of molecular sciences - 10 Nov 2023

Markovic Marko, Ranin Jovan, Bukumiric Zoran, Jerotic Djurdja, Savic-Radojevic Ana, Pljesa-Ercegovac Marija, Djukic Tatjana, Ercegovac Marko, Asanin Milika, Milosevic Ivana, Stevanovic Goran, Simic Tatjana, Coric Vesna, Matic Marija

Abstract excerpt

In SARS-CoV-2 infection, excessive activation of the immune system intensively increases reactive oxygen species levels, causing harmful hyperinflammatory and oxidative state cumulative effects which may contribute to COVID-19 severity. Therefore, we assumed that antioxidant genetic profile, independently and complemented with laboratory markers, modulates COVID-19 severity. The study included 265 COVID-19...

Topics

Humans
COVID-19
SARS-CoV-2
Genotype
Polymorphism, Genetic
Fibrinogen
Glutathione Peroxidase
Glutathione Transferase

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38003341
DOI: 10.3390/ijms242216151
PMCID: PMC10671662

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-38003341-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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