Article
Decline in HbA1c during the first year of elexacaftor/tezacaftor/ivacaftor treatment in the Danish cystic fibrosis cohort: Short title: Decline in HbA1c after elexacaftor/tezacaftor/ivacaftor treatment.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Jan 2024
Nielsen Bibi Uhre, Olsen Mette Frahm, Mabuza Mathiesen Inger Hee, Pressler Tacjana, Ritz Christian, Katzenstein Terese Lea, Olesen Hanne Vebert, Skov Marianne, Jensen-Fangel Søren, Almdal Thomas Peter, Faurholt-Jepsen Daniel
Abstract excerpt
BACKGROUND: Elexacaftor/tezacaftor/ivacaftor (ETI) has improved the clinical status of individuals with cystic fibrosis (CF), however, whether ETI impacts glucose tolerance remains unknown. We aimed to study the change in glycated hemoglobin (HbA1c) and CF related diabetes (CFRD) status after initiation of ETI. METHODS: We included individuals ≥12 years treated with ETI in Denmark in a longitudinal observational...
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