Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chronic graft-versus-host disease detected by tissue-specific cell-free DNA methylation biomarkers

16 Nov 2023

Abstract excerpt

BACKGROUND: Accurate detection of graft-versus-host disease (GVHD) is a major challenge in the management of patients undergoing hematopoietic stem cell transplantation (HCT). Here, we demonstrated the use of circulating cell-free DNA (cfDNA) for detection of tissue turnover and chronic GVHD (cGVHD) in specific organs. METHODS: We established a cocktail of tissue-specific DNA methylation markers and used it to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Cancer Genomics and Diagnostics
Share to Hematopoietic Stem Cell Transplantation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37971879
DOI: 10.1172/jci163541

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chronic graft-versus-host disease detected by tissue-specific cell-free DNA methylation biomarkersPMID 37971879Read ↗

Cell-free DNA Profiling Informs Major Complications of Hematopoietic Cell TransplantationSemantic proximity Read ↗

Chronic graft-versus-host disease is characterized by high levels and distinctive tissue-of-origin patterns of cell-free DNASemantic proximity Read ↗

Circulating cell-free DNA methylation patterns indicate cellular sources of allograft injury after liver transplantSemantic proximity Read ↗

Low Levels of Hepatocyte‐Specific Methylation in Cell‐Free DNA Are a Strong Negative Predictor for Acute T Cell–Mediated Rejection Requiring Treatment Following Liver TransplantationSemantic proximity Read ↗

Quantification of transplant-derived circulating cell-free DNA in absence of a donor genotype.Semantic proximity Read ↗

Myriad Applications of Circulating Cell-Free DNA in Precision Organ Transplant MonitoringSemantic proximity Read ↗

Graft-Derived Cell-Free DNA Quantification following Liver Transplantation Using Tissue-Specific DNA Methylation and Donor-Specific Genotyping Techniques: An Orthogonal Comparison StudySemantic proximity Read ↗

Why Cell-Free DNA Can Be a “Game Changer” for Lung Allograft Monitoring for Rejection and InfectionSemantic proximity Read ↗

Comprehensive DNA methylation analysis of tissue of origin of plasma cell-free DNA by methylated CpG tandem amplification and sequencing (MCTA-Seq)Semantic proximity Read ↗

Cell-free DNA profiling informs all major complications of hematopoietic cell transplantationSemantic proximity Read ↗

Identification of tissue-specific cell death using methylation patterns of circulating DNASemantic proximity Read ↗

Distinct Molecular Processes Mediate Donor-derived Cell-free DNA Release From Kidney Transplants in Different Disease StatesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.