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Article

Changes in ADAR RNA editing patterns in CMV and ZIKV congenital infections

15 Nov 2023

Abstract excerpt

BACKGROUND: RNA editing is a process that increases transcriptome diversity, often through Adenosine Deaminases Acting on RNA (ADARs) that catalyze the deamination of adenosine to inosine. ADAR editing plays an important role in regulating brain function and immune activation, and is dynamically regulated during brain development. Additionally, the ADAR1 p150 isoform is induced by interferons in viral infection...

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PMID: 37968596
DOI: 10.1186/s12864-023-09778-4

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