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Article

Amivantamab compared with real-world therapies in patients with advanced non-small cell lung cancer EGFR Exon 20 insertion mutations after platinum-based chemotherapy.

Acta oncologica (Stockholm, Sweden) - 1 Dec 2023

Kim Tae Min, Girard Nicolas, Low Grace Kah Mun, Zhuo Jianmin, Yu Dae Young, Yang Yishen, Murota Maiko, Lim Cindy Thiow Koon, Kleinman Nora J, Cho Byoung Chul

Abstract excerpt

BACKGROUND: In the single-arm CHRYSALIS trial, advanced non-small cell lung cancer patients harboring epidermal growth factor receptor (EGFR) exon 20 insertion (Exon 20ins) showed durable responses to amivantamab, an EGFR-MET bispecific antibody targeting tumors with EGFR Exon 20ins. This study compared the effectiveness of amivantamab to real-world systemic anti-cancer therapies in Japan. PATIENTS AND METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37938161
DOI: 10.1080/0284186X.2023.2254479

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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