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Use of Bacteriophages to Target Intracellular Pathogens

1 Nov 2023

Abstract excerpt

Bacteriophages (phages) have shown great potential as natural antimicrobials against extracellular pathogens (eg, Escherichia coli or Klebsiella pneumoniae), but little is known about how they interact with intracellular targets (eg, Shigella spp., Salmonella spp., Mycobacterium spp.) in the mammalian host. Recent research has demonstrated that phages can enter human cells. However, for the design of successful...

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PMID: 37932114
DOI: 10.1093/cid/ciad515

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