Article
Longitudinal Effects of Elexacaftor/Tezacaftor/Ivacaftor: Multidimensional Assessment of Neuropsychological Side Effects and Physical and Mental Health Outcomes in Adolescents and Adults.
Chest - 1 Apr 2024
Graziano Sonia, Boldrini Francesca, Pellicano Gaia Romana, Milo Francesco, Majo Fabio, Cristiani Luca, Montemitro Enza, Alghisi Federico, Bella Sergio, Cutrera Renato, Fiocchi Alessandro Giovanni, Quittner Alexandra, Tabarini Paola
Abstract excerpt
BACKGROUND: Italy initiated elexacaftor/tezacaftor/ivacaftor (ETI) for people with cystic fibrosis (pwCF) in July 2021. It has led to dramatic improvements in lung function, BMI, sweat chloride, and respiratory symptoms. However, few data are available on side effects or effects on a broad range of outcomes. RESEARCH QUESTION: How does ETI affect mental health, cognitive processing, neuropsychological side...
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