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Article

Neutralization of African enterovirus A71 genogroups by antibodies to canonical genogroups.

The Journal of general virology - 1 Nov 2023

Volle Romain, Luo Lingjie, Razafindratsimandresy Richter, Sadeuh-Mba Serge Alain, Gouandjika-Valisache Ionela, Horwood Paul, Duong Veasna, Buchy Philippe, Joffret Marie-Line, Huang Zhong, Duizer Erwin, Martin Javier, Chakrabarti Lisa A, Dussart Philippe, Jouvenet Nolwenn, Delpeyroux Francis, Bessaud Maël

Abstract excerpt

Enterovirus 71 (EV-A71) is a major public health problem, causing a range of illnesses from hand-foot-and-mouth disease to severe neurological manifestations. EV-A71 strains have been phylogenetically classified into eight genogroups (A to H), based on their capsid-coding genomic region. Genogroups B and C have caused large outbreaks worldwide and represent the two canonical circulating EV-A71 subtypes. Little is...

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PMID: 37909282
DOI: 10.1099/jgv.0.001911

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