Article
Genetic Polymorphism in FSCN1 rs3801004 C/G and CD44 rs353639 A/C, as Prognostic Factor in Egyptian Breast Cancer Patients.
Asian Pacific journal of cancer prevention : APJCP - 1 Oct 2023
Ibrahim Noha E, Raafat Hamed Reham Mohammad, Refaat Ahmed, Mosaad Yasser O, Mekawy Dina Mohamed
Abstract excerpt
BACKGROUND: One of the main causes of cancer-related deaths is breast cancer. Fascin-1(FSCN1) is an actin-binding protein that is present in the mesenchymal, neuronal, and endothelial cells of mammals. Patients with breast cancer have been found to have FSCN1 overexpression. CD44 is crucial for the development, invasion, and tumour spread. Therefore, we aimed to investigate the role of FSCN1&CD44 gene...
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