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Article

Primary hyperparathyroidism in patients with multiple endocrine neoplasia type 1: Impact of genotype and surgical approach on long-term postoperative outcomes.

Surgery - 1 Jan 2024

Shariq Omair A, Abrantes Vitor B, Lu Lauren Y, Tebben Peter J, Foster Trenton M, Dy Benzon M, Lyden Melanie L, Young William F, McKenzie Travis J

Abstract excerpt

BACKGROUND: Protein-truncating germline pathogenic variants in the N- and C-terminal exons (2, 9, and 10) of the MEN1 gene may be associated with aggressive pancreatic neuroendocrine tumors. However, the impact of these variants on parathyroid disease is poorly understood. We sought to investigate the effects of genotype and surgical approach on clinical phenotype and postoperative outcomes in patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37891063
DOI: 10.1016/j.surg.2023.05.044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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