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Article

Understanding the clinical course of genotype-negative MEN1 patients can inform management strategies.

Surgery - 1 Jan 2021

Pieterman Carolina R C, Hyde Samuel M, Wu Si-Yuan, Landry Jace P, Chiang Yi-Ju, Christakis Ioannis, Grubbs Elizabeth G, Fisher Sarah B, Graham Paul H, Waguespack Steven G, Perrier Nancy D

Abstract excerpt

BACKGROUND: It is unclear whether genotype-negative clinical multiple endocrine neoplasia type 1 patients derive equal benefit from prospective surveillance as genotype-positive patients. METHODS: In this retrospective cohort study, we compared genotype-negative patients with clinical multiple endocrine neoplasia type 1 with genotype-positive index cases. Primary outcome was age-related penetrance of...

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Source

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Identifiers

PMID: 32703679
DOI: 10.1016/j.surg.2020.04.067
PMCID: PMC7856683

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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