Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deep proteome coverage advances knowledge of Treponema pallidum protein expression profiles during infection

25 Oct 2023

Abstract excerpt

Comprehensive proteome-wide analysis of the syphilis spirochete, Treponema pallidum ssp. pallidum, is technically challenging due to high sample complexity, difficulties with obtaining sufficient quantities of bacteria for analysis, and the inherent fragility of the T. pallidum cell envelope which further complicates proteomic identification of rare T. pallidum outer membrane proteins (OMPs). The main aim of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Reproductive tract infections research
Share to Syphilis Diagnosis and Treatment
Share to Virology and Viral Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37880309
DOI: 10.1038/s41598-023-45219-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deep proteome coverage advances knowledge of Treponema pallidum protein expression profiles during infectionPMID 37880309Read ↗

Structural Modeling of the Treponema pallidum Outer Membrane Protein Repertoire: a Road Map for Deconvolution of Syphilis Pathogenesis and Development of a Syphilis VaccineSemantic proximity Read ↗

Functional insights from proteome-wide structural modeling of Treponema pallidum subspecies pallidum, the causative agent of syphilisSemantic proximity Read ↗

Identification of a Potential Vaccine against Treponema pallidum Using Subtractive Proteomics and Reverse-Vaccinology ApproachesSemantic proximity Read ↗

A Novel Pan-Proteome Array for High-Throughput Profiling of the Humoral Response to <i>Treponema pallidum</i> subsp. <i>pallidum</i> : a Pre-Clinical StudySemantic proximity Read ↗

Comparative genomics and full-length Tprk profiling of Treponema pallidum subsp. pallidum reinfection.Semantic proximity Read ↗

TP0326, a Treponema pallidum β‐barrel assembly machinery A (BamA) orthologue and rare outer membrane proteinSemantic proximity Read ↗

High-coverage proteome analysis reveals the first insight of protein modification systems in the pathogenic spirochete Leptospira interrogansSemantic proximity Read ↗

Comparative Genomics and Full-Length TprK Profiling of <i>Treponema pallidum</i> subsp. <i>pallidum</i> ReinfectionSemantic proximity Read ↗

Syphilis and the host: multi-omic analysis of host cellular responses to Treponema pallidum provides novel insight into syphilis pathogenesisSemantic proximity Read ↗

The genome of<i>Treponema pallidum</i>: new light on the agent of syphilisSemantic proximity Read ↗

Identification of the Treponema pallidum subsp. pallidum TP0092 (RpoE) Regulon and Its Implications for Pathogen Persistence in the Host and Syphilis PathogenesisSemantic proximity Read ↗

Genome Scale Identification ofTreponema pallidumAntigensSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.