Article
Pathologic Evaluation of Therapeutic Biomarkers in Colorectal Adenocarcinoma.
Surgical pathology clinics - 1 Dec 2023
Baranov Esther, Nowak Jonathan A
Abstract excerpt
Molecular testing is an essential component of the pathologic evaluation of colorectal carcinoma providing diagnostic, prognostic, and predictive therapeutic information. Mismatch repair status evaluation is required for all tumors. Advanced and metastatic tumors also require determination of tumor mutational burden, KRAS, NRAS, and BRAF mutation status, ERBB2 amplification status, and NTRK and RET gene...
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