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Article

Blood exosome sensing via neuronal insulin-like growth factor-1 regulates autism-related phenotypes.

Pharmacological research - 1 Nov 2023

Chen Lei, Xiong Xi-Yue, Yao Tong-Tong, Gui Lue-Ning, Luo Fan, Du Yang, Cheng Yong

Abstract excerpt

The development and progression of autism spectrum disorder (ASD) is characterized by multiple complex molecular events, highlighting the importance of the prefrontal brain regions in this process. Exosomes are nanovesicles that play a critical role in intercellular communication. Peripheral systems influence brain function under both physiological and pathological conditions. We investigated whether this...

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PMID: 37852341
DOI: 10.1016/j.phrs.2023.106965

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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