Article
A Novel Dual-labeled Peptide for Multimodal Imaging of EGFR with L858R Mutation.
Current radiopharmaceuticals - 1 Jan 2024
Kim Myoung Hyoun, Kim Seul-Gi, Kim Dae-Weung
Abstract excerpt
BACKGROUND: The development of molecular imaging agents targeting epidermal growth factor receptor (EGFR) with L858R mutation may help with the selection of non-small cell lung carcinoma (NSCLCL) patients who may benefit from EFGR tyrosine kinase inhibitor (TKI) therapy. OBJECTIVE: In this study, we developed 99mTc STHHYYP-GHEG-ECGK-tetramethylrhodamine (STHHYYP-ECGK-TAMRA) to target EGFR with L858R mutation in...
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