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Article

The genetics of pyoderma gangrenosum and implications for treatment: a systematic review.

The British journal of dermatology - 1 Jun 2015

DeFilippis E M, Feldman S R, Huang W W

Abstract excerpt

Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis characterized by painful skin ulcerations for which treatment can be challenging. The genetic basis of PG may provide a better understanding of the disease and new targets for treatment. We systematically reviewed the published literature regarding the syndromes and genetic mutations associated with PG. A literature search was performed through the...

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Identifiers

PMID: 25350484
DOI: 10.1111/bjd.13493

Genes

MTHFR
JAK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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