Article
Demethylating agents in combination with CD7-targeted CAR-T for the successful treatment of a case with mixed-phenotype acute leukemia relapsed after allogeneic hematopoietic stem cell transplantation: A Case Report.
Frontiers in immunology - 1 Jan 2023
Han Ying, Yao Hao, He Guang-Cui, Lai Si-Han, Deng Yan, Zhang Shan, He Ying, Xiong Yi-Song, Chang Alex H, Su Yi, Yi Hai
Abstract excerpt
Background: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) has cured many patients with malignant hematologic diseases such as mixed phenotype acute leukemia (MPAL), while those relapsing after allo-HSCT still exhibit high mortality, poor prognosis, and no standard treatment modalities. It is necessary to explore more therapeutic modalities for patients with post-transplant relapse to obtain a...
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