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Bacteria-derived DNA in serum extracellular vesicles are biomarkers for renal cell carcinoma

1 Sept 2023

Abstract excerpt

This is the first study to determine the clinical importance of circulating bacterial DNA in patients with renal cell carcinoma (RCC). We performed 16S rRNA metagenomic analysis of serum extracellular vesicles (EVs) from 88 patients with RCC and 10 healthy donors and identified three abundant bacterial DNA: Bacteroidia, TM7-1, and Sphingomonadales. Combining characteristic bacterial DNA information (three...

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PMID: 37810127
DOI: 10.1016/j.heliyon.2023.e19800

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