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Generation of two induced pluripotent stem cell lines from patients suffering from pulmonary hypertension.

Stem cell research - 1 Oct 2023

Chen Gaoxian, Orozco Lorena, Parmisano Sophia, Jahng James W S, Vera Carlos D, Zhuge Yan, Wu Joseph C, Obal Detlef

Abstract excerpt

Idiopathic pulmonary arterial hypertension (IPAH) is a rare disease, with an estimated 500-1000 new cases diagnosed every year. A portion of these cases may be caused by mutations in the BMPR2 gene, suggesting a possible genetic component in the development of the disease. Here, we report two human induced pluripotent stem cell (iPSC) lines generated from IPAH patients. Both cell lines provide valuable insight...

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Identifiers

PMID: 37804546
DOI: 10.1016/j.scr.2023.103218
PMCID: PMC11006094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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