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Article

A Role for Exchange of Extracellular Vesicles in Porcine Spermatogonial Co-Culture

20 Apr 2022

Abstract excerpt

Spermatogonial stem cells (SSCs) provide the basis for lifelong male fertility through self-renewal and differentiation. Prepubertal male cancer patients may be rendered infertile by gonadotoxic chemotherapy and, unlike sexually mature men, cannot store sperm. Alternatively, testicular biopsies taken prior to treatment may be used to restore fertility in adulthood. Testicular SSC populations are limited, and in...

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PMID: 35562927
DOI: 10.3390/ijms23094535

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