Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic risk score in multiple sclerosis is associated with unique gut microbiome.

Scientific reports - 27 Sept 2023

Elsayed Noha S, Valenzuela Robert K, Kitchner Terrie, Le Thao, Mayer John, Tang Zheng-Zheng, Bayanagari Vishnu R, Lu Qiongshi, Aston Paula, Anantharaman Karthik, Shukla Sanjay K

Abstract excerpt

Multiple sclerosis (MS) is a complex autoimmune disease in which both the roles of genetic susceptibility and environmental/microbial factors have been investigated. More than 200 genetic susceptibility variants have been identified along with the dysbiosis of gut microbiota, both independently have been shown to be associated with MS. We hypothesize that MS patients harboring genetic susceptibility variants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dysbiosis
Share to Gastrointestinal Microbiome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Gut microbiota and health

Share to Multiple Sclerosis

Share to Mycobacterium research and diagnosis

Share to Risk Factors

Share to RNA, Ribosomal, 16S

Source

Open in PubMed Open full text

Identifiers

PMID: 37758833
DOI: 10.1038/s41598-023-43217-4
PMCID: PMC10533555

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic risk score in multiple sclerosis is associated with unique gut microbiome.PMID 37758833Read ↗

Association Between Polygenic Risk Score And Gut Microbiome Of Multiple SclerosisSemantic proximity Read ↗

Host Genetics and Gut Microbiome: Perspectives for Multiple SclerosisSemantic proximity Read ↗

Gut microbiome and the risk factors in central nervous system autoimmunitySemantic proximity Read ↗

The Role of the Gut Microbiome in Multiple Sclerosis Risk and Progression: Towards Characterization of the “MS Microbiome”Semantic proximity Read ↗

Gut microbiome of multiple sclerosis patients and paired household healthy controls reveal associations with disease risk and courseSemantic proximity Read ↗

Multiple sclerosis patients have a distinct gut microbiota compared to healthy controlsSemantic proximity Read ↗

Interactions between host genetics and gut microbiota determine susceptibility to CNS autoimmunity.Semantic proximity Read ↗

Gut microbial factors predict disease severity in a mouse model of multiple sclerosisSemantic proximity Read ↗

Microbiota-Driven Mechanisms in Multiple Sclerosis: Pathogenesis, Therapeutic Strategies, and Biomarker PotentialSemantic proximity Read ↗

Meta-analysis identifies common gut microbiota signatures in patients with multiple sclerosisSemantic proximity Read ↗

A Metagenome-Wide Association Study of Gut Microbiome in Patients With Multiple Sclerosis Revealed Novel Disease PathologySemantic proximity Read ↗

Modulation of multiple sclerosis risk and pathogenesis by the gut microbiota: Complex interactions between host genetics, bacterial metabolism, and diet.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.