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IRF2BP2 drives lymphatic metastasis in OSCC cells by elevating mitochondrial fission‐dependent fatty acid oxidation

22 Sept 2023

Abstract excerpt

Abstract Lymph node metastasis (LNM) is a major determinant for the poor outcome of oral squamous cell carcinoma (OSCC). Interferon regulatory factor 2 binding protein 2 (IRF2BP2) has been reported to modulate the development and progression of several types of cancers, while its role in OSCC with LNM has not been reported yet. The expression of IRF2BP2 and its association with LNM were evaluated by...

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PMID: 37737489
DOI: 10.1002/mc.23635

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