Article
Biomarker Phenotypes in Heart Failure with Preserved Ejection Fraction Using Hierarchical Clustering: A Pilot Study.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre - 1 Jan 2023
Mitic Valentina, Stojanovic Dijana, Deljanin Ilic Marina, Petrovic Dejan, Ignjatovic Aleksandra, Milenkovic Jelena
Abstract excerpt
OBJECTIVES: We hypothesized the existence of distinct phenotype-based groups within the very heterogeneous population of patients of heart failure with preserved ejection fraction (HFpEF) and using an unsupervised hierarchical clustering applied to plasma concentration of various biomarkers. We sought to characterize them as "biomarker phenotypes" and to conclude differences in their overall characteristics....
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