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Article

Generation of a human iPSC line CIPi003-A from a patient with focal epilepsy harboring a heterozygous mutation in DEPDC5 gene.

Stem cell research - 1 Oct 2023

Shen Mengxiao, Fan Shiqi, Wu Fan, Cheng Peidi, Gao Yanyan, Zheng Ping, Feng Shuo, Ji Xinna, Chen Qian, Zhang Xue

Abstract excerpt

The DEPDC5 gene (OMIM 614191) has been proven to be a frequent cause of familial and sporadic focal epilepsy. A human induced pluripotent stem cell (iPSC) line was generated from a child diagnosed with focal epilepsy, which was caused by DEDPC5 mutation. The iPSC line expresses high pluripotency markers, carries the DEDPC5 mutation, and can differentiate into three germ layers in vitro. The iPSC lines offer a...

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Identifiers

PMID: 37722146
DOI: 10.1016/j.scr.2023.103195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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