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Article

Establishment and characterization of a human induced pluripotent stem cell line from a child with epilepsy.

Stem cell research - 1 Feb 2026

Jiang Wei, Chen Chuanmei, Zhang Hongwei, Zhu Shuxia

Abstract excerpt

Epilepsy is a chronic neurological disorder characterized by recurrent seizures. The condition can develop at any age, with particularly high prevalence in infancy and old age. Here, we generated a human induced pluripotent stem cell (iPSC) line from peripheral blood mononuclear cells (PBMCs) obtained from a 5-year-old girl diagnosed with epilepsy carrying a heterozygous PCDH19 mutation (c.380C > T; p.Pro127Leu)....

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Identifiers

PMID: 41496288
DOI: 10.1016/j.scr.2025.103900

Genes

PCDH19

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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