Article
Pharmacogenetic study of phosphatase and tensin homolog polymorphism (rs701848) in childhood epilepsy: relation to circulating Wnt signaling.
Neurological research - 1 Feb 2024
Hassan Mohammed H, Nassar Ahmed Y, Meki Abdel-Raheim M A, Nasser Shimaa A, Bakri Ali Helmi, Radwan Eman
Abstract excerpt
OBJECTIVE: The present study aimed at evaluating the potential contribution of Phosphatase and Tensin Homolog (PTEN) and its gene polymorphism (PTEN rs701848 T/C) in relation to Wingless/integrase-1 (Wnt) signaling in childhood epilepsy and the impact of antiepileptic medications on their serum levels. METHODS: This study included 100 children with epilepsy (50 pharmacoresistant and 50 pharmacoresponsive) and 50...
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