Article
Desmin-positivity in spindle cells: under-recognized immunophenotype of lipoblastoma.
Pathology international - 1 Jul 2013
Kubota Fumie, Matsuyama Atsuji, Shibuya Ryo, Nakamoto Mitsuhiro, Hisaoka Masanori
Abstract excerpt
Lipoblastoma is a distinct benign fatty tumor composed of adipocytes, lipoblasts, and primitive mesenchymal cells with a myxoid stroma. Lipoblastoma harbors characteristic fusion genes involving the PLAG1, resulting in aberrant expression of PLAG1. However, the nature of the primitive mesenchymal cells remains obscure. In our routine pathology practice, we noticed desmin-positive spindle mesenchymal cells in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.