Article
Conventional and genetic associations of adiposity with 1463 proteins in relatively lean Chinese adults.
European journal of epidemiology - 1 Oct 2023
Yao Pang, Iona Andri, Kartsonaki Christiana, Said Saredo, Wright Neil, Lin Kuang, Pozarickij Alfred, Millwood Iona, Fry Hannah, Mazidi Mohsen, Chen Yiping, Du Huaidong, Bennett Derrick, Avery Daniel, Schmidt Dan, Pei Pei, Lv Jun, Yu Canqing, Hill Michael, Chen Junshi, Peto Richard, Walters Robin, Collins Rory, Li Liming, Clarke Robert, Chen Zhengming
Abstract excerpt
Adiposity is associated with multiple diseases and traits, but little is known about the causal relevance and mechanisms underlying these associations. Large-scale proteomic profiling, especially when integrated with genetic data, can clarify mechanisms linking adiposity with disease outcomes. We examined the associations of adiposity with plasma levels of 1463 proteins in 3977 Chinese adults, using measured and...
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