Article
Charting the tumor microenvironment with spatial profiling technologies.
Trends in cancer - 1 Dec 2023
Toninelli Mattia, Rossetti Grazisa, Pagani Massimiliano
Abstract excerpt
In recent years technologies that can achieve readouts at cellular resolution such as single-cell RNA sequencing (scRNA-seq) have provided a comprehensive characterization of the cellular proportions and phenotypes that populate the tumor microenvironment (TME). However, because of the sample dissociation steps required by these protocols, they fail to capture information related to the intricate spatial context...
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