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Article

Pervasive under-dominance in gene expression underlying emergent growth trajectories in Arabidopsis thaliana hybrids.

Genome biology - 4 Sept 2023

Yuan Wei, Beitel Fiona, Srikant Thanvi, Bezrukov Ilja, Schäfer Sabine, Kraft Robin, Weigel Detlef

Abstract excerpt

BACKGROUND: Complex traits, such as growth and fitness, are typically controlled by a very large number of variants, which can interact in both additive and non-additive fashion. In an attempt to gauge the relative importance of both types of genetic interactions, we turn to hybrids, which provide a facile means for creating many novel allele combinations. RESULTS: We focus on the interaction between alleles of...

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PMID: 37667232
DOI: 10.1186/s13059-023-03043-3
PMCID: PMC10478501

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