Article
Heritability and recursive influence of host genetics on the rumen microbiota drive body weight variance in male Hu sheep lambs.
Microbiome - 29 Aug 2023
Wang Weimin, Zhang Yukun, Zhang Xiaoxue, Li Chong, Yuan Lvfeng, Zhang Deyin, Zhao Yuan, Li Xiaolong, Cheng Jiangbo, Lin Changchun, Zhao Liming, Wang Jianghui, Xu Dan, Yue Xiangpeng, Li Wanhong, Wen Xiuxiu, Jiang Zhihua, Ding Xuezhi, Salekdeh Ghasem Hosseini, Li Fadi
Abstract excerpt
BACKGROUND: Heritable rumen microbiota is an important modulator of ruminant growth performance. However, no information exists to date on host genetics-rumen microbiota interactions and their association with phenotype in sheep. To solve this, we curated and analyzed whole-genome resequencing genotypes, 16S rumen-microbiota data, and longitudinal body weight (BW) phenotypes from 1150 sheep. RESULTS: A variance...
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