Article
Genetic mutations and leukapheresis in acute myeloid leukemia: is there a link?
Annals of hematology - 1 Oct 2023
Corbingi Andrea, Putzulu Rossana, Massini Giuseppina, Colangelo Maria, Minnella Gessica, Chiusolo Patrizia, Sica Simona, Piccirillo Nicola
Abstract excerpt
Acute myeloid leukemia is the most common acute leukemia in adults and up to 20% of patients present with hyperleukocytosis at the onset of the disease. The therapeutic approach involves medical support, cytoreductive treatment, and/or leukapheresis. Despite WBC count greater than 100.000/μL, not all patients develop symptoms. To clarify the role of leukapheresis in the setting of hyperleukocytotic AML, we aimed...
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