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Single-cell sequencing provides insights into the landscape of ovary in PCOS and alterations induced by CUMS

16 Aug 2023

Abstract excerpt

In this study, we mapped the landscape of polycystic ovary syndrome (PCOS) ovary with rat model induced by letrozole and provided a novel insight into the molecular mechanism of PCOS accompanied by chronic unpredicted mild stress (CUMS) at single-cell transcriptomic level. These observations highlight the importance of inflammation in the pathogenesis of PCOS, which might also be the bridge between PCOS and...

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Share to Ovarian cancer diagnosis and treatment
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37584608
DOI: 10.1152/ajpendo.00165.2023

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