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Matrikines in kidney ageing and age-related disease

10 Aug 2023

Abstract excerpt

PURPOSE OF REVIEW: Matrikines are cell-signalling extracellular matrix fragments and they have attracted recent attention from basic and translational scientists, due to their diverse roles in age-related disease and their potential as therapeutic agents. In kidney, the matrix undergoes remodelling by proteolytic fragmentation, so matrikines are likely to play a substantial, yet understudied, role in ageing and...

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PMID: 37584348
DOI: 10.1097/mnh.0000000000000916

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