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Maternal-derived galectin-1 shapes the placenta niche through Sda terminal glycosylation: Implication for preeclampsia

1 Aug 2023

Abstract excerpt

Placental abnormalities cause impaired fetal growth and poor pregnancy outcome (e.g. preeclampsia [PE]) with long-lasting consequences for the mother and offspring. The molecular dialogue between the maternal niche and the developing placenta is critical for the function of this organ. Galectin-1 (gal-1), a highly expressed glycan-binding protein at the maternal-fetal interface, orchestrates the maternal...

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Birth, Development, and Health
Pregnancy and preeclampsia studies
Reproductive System and Pregnancy

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37575671
DOI: 10.1093/pnasnexus/pgad247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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