miRNA-103-3p-Hlf Regulates Apoptosis and Autophagy by Targeting Hepatic Leukaemia Factor in Heart Failure

Abstract excerpt

AIMS: Cardiomyocyte apoptosis is an important factor leading to the occurrence and development of heart failure (HF), which is associated with high mortality of patients with cardiovascular diseases. This study aims to investigate the underlying mechanisms of HF in terms of expression and regulation patterns using bioinformatics and experimental validation. METHODS AND RESULTS: Two HF datasets were collected: a...

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