Article
Detection of resistance to second-line antituberculosis drugs by use of the genotype MTBDRsl assay: a multicenter evaluation and feasibility study.
Journal of clinical microbiology - 1 May 2012
Ignatyeva Olga, Kontsevaya Irina, Kovalyov Alexander, Balabanova Yanina, Nikolayevskyy Vladislav, Toit Kadri, Dragan Anda, Maxim Daniela, Mironova Svetlana, Kummik Tiina, Muntean Ionela, Koshkarova Ekaterina, Drobniewski Francis
Abstract excerpt
The rate of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) has been steadily increasing in countries of the former USSR. The availability of rapid and reliable methods for the detection of drug resistance to second-line drugs is vital for adequate patient management. We evaluated the performance of the Genotype MTBDRsl assay compared to that of phenotypic drug susceptibility...
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