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The effects of amino acid substitution of spike protein and genomic recombination on the evolution of SARS-CoV-2

25 Jul 2023

Abstract excerpt

Over three years' pandemic of 2019 novel coronavirus disease (COVID-19), multiple variants and novel subvariants have emerged successively, outcompeted earlier variants and become predominant. The sequential emergence of variants reflects the evolutionary process of mutation-selection-adaption of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Amino acid substitution/insertion/deletion in the spike...

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PMID: 37560529
DOI: 10.3389/fmicb.2023.1228128

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