Article
Impact of intrinsic and extrinsic risk factors on early-onset lung disease in cystic fibrosis.
Pediatric pulmonology - 1 Nov 2023
Huang Leslie, Lai HuiChuan J, Song Jie, Zhao Zijie, Lu Qiongshi, Murali Sangita G, Brown Donna M, Worthey Elizabeth A, Farrell Philip M
Abstract excerpt
BACKGROUND: Although respiratory pathology is known to develop in young children with cystic fibrosis (CF), the determinants of early-onset lung disease have not been elucidated. OBJECTIVE: We aimed to determine the impact of potential intrinsic and extrinsic risk factors during the first 3 years of life, testing the hypothesis that both contribute significantly to early-onset CF lung disease. DESIGN: We studied...
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