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Copper homeostasis-associated gene PRNP regulates ferroptosis and immune infiltration in breast cancer

3 Aug 2023

Abstract excerpt

Breast cancer (BRCA) is one of the most common cancers in women. Copper (Cu) is an essential trace element implicated in many physiological processes and human diseases, including BRCA. In this study, we performed bioinformatics analysis and experiments to determine differentially expressed copper homeostasis-associated genes in BRCA. Based on two Gene Expression Omnibus (GEO) datasets, the copper...

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PMID: 37535656
DOI: 10.1371/journal.pone.0288091

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