Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Evaluation of Ferroptosis-related Gene AKR1C1 as a Novel Biomarker Associated with the Immune Microenvironment and Prognosis in Breast Cancer

1 Sept 2021

Abstract excerpt

Background: Ferroptosis is the latest-discovered, iron-dependent form of regulated cell death. It has been increasingly recognized that ferroptosis-related genes participate in oncogenesis and development of cancers, including breast cancer ( BRCA ). Thus, It is important to explore the biofunctions of ferroptosis-related genes in BRCA . Methods: Transcriptome microarray datasets (GSE22358, GSE9014 and GSE8977,...

Source

Identifiers

PMID: 34611432
DOI: 10.2147/ijgm.s329031

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of Ferroptosis-related Gene AKR1C1 as a Novel Biomarker Associated with the Immune Microenvironment and Prognosis in Breast CancerPMID 34611432Read ↗

The role of ferroptosis in breast cancer patients: a comprehensive analysisSemantic proximity Read ↗

Identification and validation of a ferroptosis-related gene signature predictive of prognosis in breast cancerSemantic proximity Read ↗

Identification of the prognostic value of ferroptosis-related gene signature in breast cancer patientsSemantic proximity Read ↗

A ferroptosis-associated gene signature for the prediction of prognosis and therapeutic response in luminal-type breast carcinomaSemantic proximity Read ↗

Integrative analysis of the molecular mechanisms, immunological features and immunotherapy response of ferroptosis regulators across 33 cancer typesSemantic proximity Read ↗

Novel Ferroptosis-related gene signature for predicting the prognosis of breast cancerSemantic proximity Read ↗

The prognostic significance of a novel ferroptosis-related gene model in breast cancerSemantic proximity Read ↗

A ferroptosis-associated gene signature for the prediction of prognosis and therapeutic response in luminal-type breast carcinomaSemantic proximity Read ↗

A Novel Ferroptosis-Related Gene Signature for Overall Survival Prediction in Patients With Breast CancerSemantic proximity Read ↗

Application of single-cell RNA sequencing analysis of novel breast cancer phenotypes based on the activation of ferroptosis-related genes.Semantic proximity Read ↗

Comprehensive analysis regarding the prognostic significance of downregulated ferroptosis-related gene AKR1C2 in gastric cancer and its underlying roles in immune responseSemantic proximity Read ↗

Identification of key ferroptosis genes and mechanisms associated with breast cancer using bioinformatics, machine learning, and experimental validationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.